FACTS ABOUT OXYCODONE HYDROCHLORIDE REVEALED

Metabolism: Oxycodone hydrochloride is extensively metabolized to noroxycodone, oxymorphone, as well as their glucuronides. The most important circulating metabolite is noroxycodone with an AUC ratio of 0.The concomitant use of OXYCONTIN and CYP3A4 inhibitors can increase the plasma focus of oxycodone, resulting in amplified or prolonged opioid out